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KMID : 0358419920350121742
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Korean Journal of Obstetrics and Gynecology
1992 Volume.35 No. 12 p.1742 ~ p.1748
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The Impact of Genetic Counseling on Performance of Prenatal Cytogenetic Diagnosis
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김세광/Kim SK
양영호/송찬호/Yang YH/Song CH
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Abstract
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Analysis of prenatal genetic services was undertaken to identify the influence of genetic counseling on performance of prenatal cytogenetic diagnosis. From September 1, 1990 to September 30, 1991, there were 2,255 ddeliveries at Severance Hospital, Yonsei University College of Medicine, of which 190 (8.4%) patients had indications for prenatal cytogenetic diagnosis. The most common indication for prenatal cytogenetic diagnosis was advanced maternal age(75.8%). The rate of acceptance of prenatal cytogenetic tests in patiens who had indications was very low(26.3%). The main reasons for patients not receiving prenatal cytohenetic tests were omission of genetic counseling (67.1%) and late registration (16.4%). Every obstetrician should provide appropriate genetic counseling to eheir patients who have increased risk of having a fetus with chromosmal abnormalities. Screening for fetal chromosomal abnormality with maternal serum markers such as alpha-fetoprotein, unconjugated estriol, human chorionic gonadotropin should be prososed during genetic counseling for women under 35. A liberal application of rapid cytogenetic tests such as cordocentesis or transabdominal placental biopsy in the late second or early third trimesters of pregnancy also be considered for patients who register late.
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KEYWORD
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